Comparative metal oxide nanoparticle toxicity using embryonic zebrafish
نویسندگان
چکیده
منابع مشابه
Comparative metal oxide nanoparticle toxicity using embryonic zebrafish
Engineered metal oxide nanoparticles (MO NPs) are finding increasing utility in the medical field as anticancer agents. Before validation of in vivo anticancer efficacy can occur, a better understanding of whole-animal toxicity is required. We compared the toxicity of seven widely used semiconductor MO NPs made from zinc oxide (ZnO), titanium dioxide, cerium dioxide and tin dioxide prepared in ...
متن کاملInfluence of surface chemical properties on the toxicity of engineered zinc oxide nanoparticles to embryonic zebrafish
Zinc oxide nanoparticles (ZnO NPs) are widely used in a variety of products, thus understanding their health and environmental impacts is necessary to appropriately manage their risks. To keep pace with the rapid increase in products utilizing engineered ZnO NPs, rapid in silico toxicity test methods based on knowledge of comprehensive in vivo and in vitro toxic responses are beneficial in dete...
متن کاملMetal nanoparticle catalysts decorated with metal oxide clusters.
Au nanoparticles decorated with mononuclear Ti-oxo units dispersed in silica clusters were formed by activating Au nanoparticles (~2 nm) stabilized with Ti- and amine-functionalized siloxane oligomers. These Au nanoparticles were active catalysts for selective oxidation of propane to acetone, and the activity increased with increasing Ti density.
متن کاملZebrafish: A complete animal model to enumerate the nanoparticle toxicity
Presently, nanotechnology is a multi-trillion dollar business sector that covers a wide range of industries, such as medicine, electronics and chemistry. In the current era, the commercial transition of nanotechnology from research level to industrial level is stimulating the world's total economic growth. However, commercialization of nanoparticles might offer possible risks once they are libe...
متن کاملComparative hazard analysis and toxicological modeling of diverse nanomaterials using the embryonic zebrafish (EZ) metric of toxicity
The integration of rapid assays, large datasets, informatics, and modeling can overcome current barriers in understanding nanomaterial structure-toxicity relationships by providing a weight-of-the-evidence mechanism to generate hazard rankings for nanomaterials. Here, we present the use of a rapid, low-cost assay to perform screening-level toxicity evaluations of nanomaterials in vivo. Calculat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Toxicology Reports
سال: 2015
ISSN: 2214-7500
DOI: 10.1016/j.toxrep.2015.03.015